NAC

N-Acetyl-L-Cysteine (NAC) is known to have diverse physiological and therapeutic benefits, attributed largely to its antioxidant, anti-inflammatory and mucolytic effects. It is well-accepted to increase the critical intracellular antioxidant glutathione, by supplying a stable form of L-cysteine, the rate-limiting factor for glutathione synthesis. The number of conditions with altered glutathione homeostasis continues to grow, including not only cardiovascular, neurodegenerative, pulmonary and age-related diseases, but there is also a growing clinical recognition of metabolic disturbances linked to environmental toxin exposure, such as diabetes and persistent organic pollutants. By restoring glutathione levels, NAC also is well established as the most effective therapy for acetaminophen toxicity.